Light cigarette smoke‐induced emphysema and NFkB activation in mouse lung
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چکیده
منابع مشابه
Congenital Cyst and Emphysema of the Lung
Les auteurs rapportent chez deux nourrissons, l'etude anatomo-clinique d'un cas de kystes alveolaires multiples,et d'un cas d'emphyseme lobaire congenital bilateral.Le troisieme cas concerne un kyste bronchog6nique du poumon gauche,decouvert a l'autopsie d'un nouveau-ne. Dans le quatrieme cas,un emphyseme geant du lobe superieur gauche,decouvert dans un contexte infectieux,a l'age de neuf mois,...
متن کاملCigarette smoking, asthma, and emphysema.
1 Light RW, Cheng DS, Lee YC, et al. A single intrapleural injection of transforming growth factor(2) produces an excellent pleurodesis in rabbits. Am J Respir Crit Care Med 2000; 162:98–104 2 Lee YC, Lane KB, Parker RE, et al. Transforming growth factor (2) (TGF (2)) produces effective pleurodesis in sheep with no systemic complications. Thorax 2000; 55:1058–1062 3 Gary Lee YC, Teixeira LR, De...
متن کاملComparison between cigarette smoke-induced emphysema and cigarette smoke extract-induced emphysema
BACKGROUND AND OBJECTIVE Emphysema is the main pathological feature of COPD and also is the focus of the related research. Although several emphysema animal models have been established, exact comparison of findings is seldom. The present study aimed to compare cigarette smoke (CS) exposure-induced emphysema model and intraperitoneal injection of cigarette smoke extract (CSE)-induced emphysema ...
متن کاملPersistence of lung CD8 T cell oligoclonal expansions upon smoking cessation in a mouse model of cigarette smoke-induced emphysema.
The role of adaptive immunity in the development or progression of chronic obstructive pulmonary disease (COPD) remains undefined. Recently, the presence of autoantibodies and autoreactive T cells has been demonstrated in COPD patients. In addition, oligoclonal expansions of lung T cells have been observed in COPD patients, but the overlapping incidence of infections, tumors, and cigarette smok...
متن کاملmTOR pathway activation drives lung cell senescence and emphysema.
Chronic obstructive pulmonary disease (COPD) is a highly prevalent and devastating condition for which no curative treatment is available. Exaggerated lung cell senescence may be a major pathogenic factor. Here, we investigated the potential role for mTOR signaling in lung cell senescence and alterations in COPD using lung tissue and derived cultured cells from patients with COPD and from age- ...
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ژورنال
عنوان ژورنال: The FASEB Journal
سال: 2006
ISSN: 0892-6638,1530-6860
DOI: 10.1096/fasebj.20.5.a1097-a